The series re-imagines the comic books main characters (Martin Mystery and Diana Lombard) as 16-year-old step-siblings attending Torrington Academy, a high school in Sherbrooke, Quebec. They work for a covert organization referred to as “The Center”, which covertly protects the people of Earth from supernatural threats. As a covert organization, their work must be kept secret and for this reason, anyone who comes too close to their missions will have their memories of the event erased.